They will select a new primary leader, but they are organized more as a confederation than a centrally controlled group. Very little of their action relies on there being a leader at all. Past Israeli assassinations of their leaders haven’t weakened the group, and I don’t see any reason this time would be different.
Their utility in both sexual and nonsexual applications makes coverage for just one use impractical. Soil testing machines and powdered metal formers use condoms to contain the loose material in the pressure vessel. They make hilarious balloons. They can keep gunpowder dry in combat.
I interned at a reseach lab that had powdered metal machines that used condoms. For a while, condoms were available as an open stores item. They pulled them due to way more being consumed than made sense for the amount of powdered metal research.