Debbie*

My wife and I usually plan big vacations about a year in advance so that we can follow flight prices and whatnot to get a good deal. We also book a few days at a cabin for our anniversary every year, so we just book the next year’s reservation while we’re there, since reservations can fill up even several months in advance.

Only planning a week in advance seems stressful to me - we planned a last-minute (for us) road trip vacation earlier this month for the long 4th of July weekend, and it was tough to find cheap places to stay that weren’t super grungy.

I didn’t really see people mentioning that “would” can still be used past-tense outside of “would have,” though it’s not in the same way - you use it when talking about something that happened multiple times in the past. For example, “When I was a kid my friends and I would go to the pool every Saturday,” which means that, as children, my friends and I did visit the pool every Saturday.

I mean, the bleak thing is that the world works through people making deals with murderers to not be murdered, instead allowing other people to be murdered. I don’t give a shit about her gender, I just want a story about a good person winning in spite of corruption, not a bad person winning because of it.

As bleak as it is, given the high amount of other political opponents that died, the fact that she didn’t is likely an indication of how nice she plays with the people doing the murdering. I’m hopeful that she’s just good at dodging assassins, though!

Makes sense. I’ve always been disappointed that instead of using better processing power to make bigger, more complex games, we used it to make the same games with more complex animations and details. I don’t want a game that only differs from its predecessors through use of graphical upgrades like individual blades of grass swaying in the wind, or the character starting to sweat in relation to their exertion; I want games with PS1-PS2 graphics and animation quality, but with complex gameplay that the consoles of that era could only dream of being able to handle.

This looks really cool - I put in my beta tester registration!

Well, yes, but that’s kinda my point. If you don’t patent, you get exploited, like how the discoverers of insulin synthesis decided not to patent, so companies patented similar, but not exact methods, and now it’s incredibly expensive. But, as you said, if you do patent, there is still a risk of exploitation if the patent holder sells to an exploitative company. However, that exploitation is still less likely than when not patenting, so I support the practice so long as patenting is still possible.

I worked at a small nonprofit back when genes were still able to be patented; we mostly studied the condition Pseudoxanthoma Elasticum, and held the patents to a few of the genes associated with it. However, we still allowed people to research them freely - we only patented them to prevent a company like Myriad Genetics, who had been patenting genes so that they could sell expensive genetic tests, from patenting it instead. We celebrated when genes were no longer able to be patented; I imagine that the researchers working with golden rice will do the same if we’re ever lucky enough for GMO’s to no longer be able to be patented.

I wholeheartedly agree. I was working for a small genetics nonprofit when they removed the ability to patent genes, and the whole office had a party to celebrate. It was mostly a celebration about freedom to research and test, but we were also very excited to no longer have to deal with having a bunch of patents. Even though we let people research the genes freely, we still had a bunch of paperwork that needed to be done any time someone wanted to do so.

Selection technically isn’t modification, since the modification had to have already occurred for it to be selected for. However, modification certainly did occur, and all crops are genetically modified. Indeed, all living creatures are genetically modified, as without modification, evolution can’t occur.

The public fear of GMO’s is largely due to Monsanto, who aggressively protect their GMO crop patents to the point where farmers who just happened to have some seeds blow into their fields have been sued.

The issue with GMO’s isn’t the modification, it’s the lax patent laws that allow companies like Monsanto to exploit people for profit, giving a bad name to the field as a whole, in spite of the immense potential good it can do, for which Golden Rice is a prime example.

The huge difference is who holds the patent. The example you gave involves Monsanto, the patent holder for several GMO crops, and a terrible company that does everything in its power to make money by exploiting people. Golden Rice, however, is patented by the scientists who designed it, who likely only patented it so that a company like Monsanto couldn’t just make some similar GMO and patent it instead, using it to exploit people even more.

This same thing happened back when genes themselves were able to be patented; some companies like Myriad Genetics would patent genes like the BRCA gene, a common source of inherited breast cancer predisposition, so that they could charge an arm and a leg for testing. So, researchers and non-profits would patent genes that they found just ensure they could be fairly studied and tested for.

The issue with the high-paying medical profession is that it attracts 2 kinds of people: nice people who want to do good and help people, and self-centered people who want to feel powerful and in-control while making a bunch of money. The latter are the reason for shit like this. I’d bet that she doesn’t care about children at all, and just wants to feel powerful, while raking in the cash from rich people looking to use her license to validate their terrible behavior.

You’d think so, right?

Negative change worms it’s way in through small defeats. The first DLC’s were a small price for a lot of content, the first YouTube ads were only a single ad that was just a few seconds long, the first video game preorders came with amazing rewards, etc. When you allow for 2 seconds, then what’s 3 seconds? What’s 4, 5, 6? What’s 30 seconds? What’s 2 minutes? We’ve seen examples of this all throughout capitalism’s history; to ignore them is, well, ignorant.

I’m definitely in support of A, regardless. I only know complex words from having seen them used correctly in the wild; how could anyone be expected to learn them otherwise?

The ability to find an approximate definition of a new word using context - and slowly whittle it down to the actual definition over subsequent encounters - is invaluable for gaining better language comprehension.

They’ve never needed pictures before, and they don’t need pictures now. Hell, even the iconic meme picture is taken from a video of a woman speaking normally - they just used an unflattering frame to discredit her. This isn’t a ploy to get a photo op of the left being mad, it’s another small push of the republican boundaries. Enough “joke” bills about overbearing punishments for minor offenses made by people their party doesn’t like, and they’ll be primed enough to fully support the real thing. We’re already there for a large portion of the republican base.

Hmm… Man seemingly dies, goes into a small space with hard walls, comes back a little while later with the ability to fly… Is Jesus mothman?

Yeah, if anything, I expect people to book whatever flights they were already going to book, and just crack jokes like “I hope I make it!”

I haven’t heard anyone irl talking about Boeing recently, and barely even saw anything online a week after the initial death. While it pisses me off to no end, this incident will blow over just as easily for Boeing.

Nobody needs a friend so badly that they’re justified in making friends with a genocidal maniac. I understand that Israel has been a long-term investment, but the amount of human suffering going on right now vastly outweighs any lamentations about sunk cost. What this country needs is a president willing to show that he cares about preventing suffering above all else. Doctors take an oath to both do good and do no harm - it’s time for our presidents to do the same, and be held to it to the same degree.